Our group is striving to address challenges related to sustainability that are of social, economic, and environmental interest. Chemical synthesis is an indispensable tool for constructing new substances or building blocks; nevertheless, it raises fundamental considerations regarding efficacy, selectivity, availability and environmental issues. The main research line in our group is the development of new non-metallic reagents and catalysts, the study of their mode of action, and their use for synthesis and asymmetric homogeneous catalysis. For this purpose, we harness mainly “unconventional” supramolecular interactions based on s-hole and metal-like behavior for developing new complementary tools in organic chemistry and unlocking new catalytic alternatives.