Robin Weiss was born in Strasbourg. He graduated in chemistry in 2016 from the University of Montpellier, France, and carried out MSc studies at the University of Strasbourg, France, studying molecular and supramolecular chemistry. After completing a preparation for Agrégation of Chemistry during one year, he pursued doctoral studies in the group of Prof. Patrick Pale at the University of Strasbourg. In early 2021, he completed his PhD degree dedicated to the study of σ-hole interactions in solution.

Then, he occupied a postdoctoral position in the group of Prof. Aloïs Fürstner in the Max-Planck Institut für Kohlenforschung, Germany. There, he developed novel gem-hydrogenation methodology based on ruthenium-vinyl carbenes for C-H activation. In 2022, he moved back to Strasbourg , where he joined the group of Prof. Loïc Jierry at the Institut Charles Sadron, France. During this time, he worked in the field of soft-mechanochemistry, studying at the molecular level mechanotransduction mechanisms upon a mechanical macroscopic stimulus.

In early 2024, he began an independent career as a Junior Professor at the University of Caen Normandie in the Laboratoire de Chimie Moléculaire et Thio-organique, where he holds a Chair of Organic Chemistry.